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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HLTF
All Species:
13.33
Human Site:
T451
Identified Species:
22.56
UniProt:
Q14527
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14527
NP_003062.2
1009
113929
T451
L
T
S
S
V
P
T
T
K
K
K
M
L
K
K
Chimpanzee
Pan troglodytes
XP_001138277
1009
113822
T451
L
T
S
S
V
P
T
T
K
K
K
M
L
K
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534300
1106
124184
T548
L
I
S
S
T
P
A
T
K
R
R
M
L
K
K
Cat
Felis silvestris
Mouse
Mus musculus
Q6PCN7
1003
113298
T445
L
T
F
F
A
S
A
T
Q
R
K
M
L
K
K
Rat
Rattus norvegicus
NP_001099948
974
110023
L416
G
K
L
K
N
T
Q
L
D
T
K
S
K
V
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508504
884
99044
T406
K
Q
D
V
V
L
T
T
Y
N
V
L
T
Y
D
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001090145
999
112576
V441
L
S
G
F
P
T
T
V
R
K
Q
K
H
K
K
Zebra Danio
Brachydanio rerio
XP_693071
942
104740
L431
L
S
V
L
S
N
W
L
D
Q
F
E
Q
H
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P34739
1061
118357
D499
K
D
E
S
S
D
S
D
S
E
D
D
K
N
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786706
1093
121576
S527
G
P
S
P
P
N
I
S
V
P
G
P
S
K
P
Poplar Tree
Populus trichocarpa
XP_002308876
799
88908
E321
E
R
T
R
E
V
E
E
L
K
K
H
D
I
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FF61
881
98598
M403
T
D
D
V
N
E
L
M
K
Y
D
I
V
L
T
Baker's Yeast
Sacchar. cerevisiae
P31244
790
91412
H312
F
K
Q
P
S
V
L
H
N
I
D
F
Y
R
V
Red Bread Mold
Neurospora crassa
Q7S1P9
1222
137173
A609
V
A
I
K
A
R
E
A
G
P
T
S
V
N
N
Conservation
Percent
Protein Identity:
100
99.5
N.A.
85.5
N.A.
83.6
81.4
N.A.
71.7
N.A.
64.3
53.1
N.A.
21.1
N.A.
N.A.
34.5
Protein Similarity:
100
99.8
N.A.
88
N.A.
89.7
87.9
N.A.
78.5
N.A.
79.3
69.8
N.A.
41.2
N.A.
N.A.
53.1
P-Site Identity:
100
100
N.A.
66.6
N.A.
53.3
13.3
N.A.
20
N.A.
33.3
6.6
N.A.
13.3
N.A.
N.A.
13.3
P-Site Similarity:
100
100
N.A.
80
N.A.
66.6
13.3
N.A.
26.6
N.A.
53.3
20
N.A.
26.6
N.A.
N.A.
20
Percent
Protein Identity:
33.6
N.A.
N.A.
36
22.7
25.2
Protein Similarity:
50.4
N.A.
N.A.
52.7
40.9
43.9
P-Site Identity:
13.3
N.A.
N.A.
6.6
0
0
P-Site Similarity:
20
N.A.
N.A.
20
6.6
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
15
0
15
8
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
15
15
0
0
8
0
8
15
0
22
8
8
0
8
% D
% Glu:
8
0
8
0
8
8
15
8
0
8
0
8
0
0
0
% E
% Phe:
8
0
8
15
0
0
0
0
0
0
8
8
0
0
0
% F
% Gly:
15
0
8
0
0
0
0
0
8
0
8
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
8
8
8
0
% H
% Ile:
0
8
8
0
0
0
8
0
0
8
0
8
0
8
8
% I
% Lys:
15
15
0
15
0
0
0
0
29
29
36
8
15
43
50
% K
% Leu:
43
0
8
8
0
8
15
15
8
0
0
8
29
8
0
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
29
0
0
0
% M
% Asn:
0
0
0
0
15
15
0
0
8
8
0
0
0
15
8
% N
% Pro:
0
8
0
15
15
22
0
0
0
15
0
8
0
0
8
% P
% Gln:
0
8
8
0
0
0
8
0
8
8
8
0
8
0
0
% Q
% Arg:
0
8
0
8
0
8
0
0
8
15
8
0
0
8
0
% R
% Ser:
0
15
29
29
22
8
8
8
8
0
0
15
8
0
0
% S
% Thr:
8
22
8
0
8
15
29
36
0
8
8
0
8
0
8
% T
% Val:
8
0
8
15
22
15
0
8
8
0
8
0
15
8
15
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
8
0
0
8
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _